Assistant Professor of Pediatrics, Hematology and Oncology
Melissa Mavers grew up in St. Louis, Missouri and completed her undergraduate degree in Microbiology and Immunology at the University of Miami. She then entered MD/PhD training at Saint Louis University where she completed her graduate studies in the laboratory of Harris Perlman, PhD. For her thesis research, she demonstrated a novel role for the cyclin-dependent kinase inhibitor p21 in suppressing macrophage activation and inflammation. Following Pediatrics residency at UCLA and Pediatric Hematology/Oncology fellowship at Stanford, she completed post-doctoral research in the laboratory of Robert Negrin, MD, at Stanford. In this work, she demonstrated that expansion and activation of regulatory T cells through death receptor 3 leads to a reduction in acute graft-versus-host disease in murine preclinical models. In 2022, Mavers joined the Department of Pediatrics at Washington University where she continues to focus her research on immune regulation of graft-versus-host disease. Outside of the lab, she enjoys supporting the Cardinals, going to festivals, and traveling.